USA > Ohio > Hancock County > Findlay > Twentieth Century History of Findlay and Hancock County, Ohio, and Representative Citizens > Part 80
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of Electro-Therapeutics. By William James Dugan, With ninety-one illustrations. 1910. 8º. 242 pages. vis Company, Philadelphia.
f Laboratory Diagnosis. By Francis Ashley Faught, Second revised edition. Containing an indican scale s, eight full-page plates and numerous engravings in .. 1910. 8vo. 336 pages. F. A. Davis Company, phia.
f Physiology. With Practical Exercises. By G. N. M. A., D. Sc., M. D. Edin., D. P. H. Camb. With col- :es and 450 other illustrations. Sixth edition. 1910. 4 pages. William Wood and Company, New York.
in Orthopedic Surgery. By Royal Whitman, M. D. dition, revised and enlarged. Illustrated with six and one engravings. 1910. 8vo. 908 pages. Lea r, Philadelphia and New York.
Opératoire. Par Henri Hartmann. Avec 422 figures exte dont 80 en couleur. 1911. 4to. 498 pages. G. Paris.
Cause and Treatment. By R. W. Murray, F. R. C. S. ition. With 62 illustrations. 1910. 8vo. 184 pages. hurchill, London.
Syndesmology. By Howard A. Sutton, A. B., M. D. K. Drinker, B. S. 1910. 8vo. 225 pages. P. s Son & Co., Philadelphia.
Measures Taken Against Malaria in the Lahore .) Cantonment. By the Hon'ble Mr. R. Nathan, C. S., Lieutenant-Colonel H. B. Thornhill, C. I. E., Major L. Rogers, M. D., F. R. C. P., F. R. C. S., 09. 8vo. Fol. 55 pages. 1910. Superintendent it Printing, Calcutta, India.
the Sixteenth Annual Convention of the American Superintendents of Training Schools for Nurses. w York, May 16 and 17, 1910, and in conjunction ssociated Nurses' Alumna of the United States, torium in the Horace Mann School, May 18, 1910. ages. J. H. Furst Company, Baltimore.
Diseases of the Stomach and Upper Alimentary Tract. By Anthony Bassler, M. D. Copiously illustrated with numerous half-tone and line text-engravings and 56 full-page half-tone plates (with nearly 100 figures) plain and in colors, from original photographs and drawings. 1910. 8vo. 836 pages. F. A. Davis Company, Philadelphia.
Oxford Medical Publications. Publishers: Henry Frowde, Lon- don; Hodder & Stoughton, London. The following four volumes.
Fractures and Their Treatment. By J. Hogarth Pringle, M. B. (Ed.), F. R. C. S. (Eng.) Glasgow. 1910. Svo. 384 pages.
A Handbook of the Surgery of Children. By E. Kirmisson. Translated by J. Keogh Murphy, M. C. (Cantab.), F. R. C. S. 1910. 8vo. 822 pages.
A System of Syphilis. In Six Volumes. Edited by D'Arcy Power, M. B. Oxon., F. R. C. S., and J. Keogh Murphy, M. C. Cantab., F. R. C. S. With an Introduction by Sir Jonathan Hutchin- son, F. R. S. Vols. V and VI. 1910. 8vo.
Practical Physiological Chemistry. A Book Designed for Use in Courses in Practical Physiological Chemistry in Schools of Medicine and of Science. By Philip B. Hawk, M. S., Ph. D. Third edition, revised and enlarged. With two full-page plates of absorption spectra in colors, four additional full- page color plates and one hundred and twenty-seven figures of which twelve are in colors. 1910. 8vo. 440 pages. P. Blakiston's Son & Co., Philadelphia.
Rational Hydrotherapy. A Manual of the Physiological and Therapeutic Effects of Hydriatic Procedures, and the Tech- nique of their Application in the Treatment of Disease. By J. H. Kellogg, M. D. With two hundred and ninety-three illustrations, nineteen in colors. Fourth revised edition. 1910. Svo. 1247 pages. F. A. Davis Company, Philadelphia.
Die Faeces des Säuglings und des Kindes. Die Bedeutung und Technik ihrer Untersuchung. Von Dr. Adolf F. Hecht. Mit einen Vorwort von Hofrat Prof. Dr. Th. Escherich. 1910. 4to. 186 pages. Urban & Schwarzenberg, Berlin and Wien. Andreas Vesalius, the Reformer of Anatomy. By James Moores Ball, M. D. 1910. Fol. XVII + 149 pages. Science Medical Press, Saint Louis.
Golden Rules of Refraction. By Ernest E. Maddox, M. D., F. R. C. S. Ed. "Golden Rules " Series. No. XII. Third edition, revised. 32mo. 96 pages. John Wright & Sons, Ltd., Bristol; Simpkin, Marshall, Hamilton, Kent & Co., Ltd., London.
Chronicles of Pharmacy. By A. C. Wootton. Two Volumes. 1910. 8vo. Macmillan and Company, Limited, London.
Applied Anatomy. The Construction of the Human Body Con- sidered in Relation to its Functions, Diseases and Injuries. By Gwilym G. Davis. With six hundred and thirty illustra- tions, mostly from original dissections and many in color by Erwin F. Faber. [1910.] 4to. 630 pages. J. B. Lippincott Company, Philadelphia and London.
The Classification and Treatment of Diseases Commonly Known as Rheumatism. By Frank E. Peckham, M. D. Fiske Fund Prize Dissertation. No. LIII. 1910. 8vo. 76 pages. Snow & Farnham Company, Printers, Providence.
The Harvey Lectures. Delivered under the Auspices of The Harvey Society of New York, 1908-1909. By Prof. A. Calmette, Prof. W. G. MacCallum, Prof. Graham Lusk, Prof. W. Falta, Dr. John F. Anderson, Dr. M. J. Rosenau, Prof. A. B. Mac- allum, Prof. J. B. Leathes, Prof. Philip Hanson Hiss, Jr., Dr. C. B. Davenport. 1910. 8vo. 290 pages. J. B. Lippincott Company, Philadelphia and London.
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Bier's Text-Book of Hyperamia as Applied in Medicine and Sur gery. By Professor Dr. August Bier. Only authorized trans- lation from the sixth German revised edition by Dr. Gustavus" M. Blech. With thirty-nine illustrations. [1909.] 8vo. 439} pages. Rebman Company, New York.
A Laboratory Text-Book of Embryology. By Charles Sedgwickt Minot, LL. D. (Yale and Toronto), D. Sc. (Oxford). Second edition, revised with 262 illustrations, chiefly original. 19103 4to. 402 pages. P. Blakiston's Son & Co., Philadelphia.
Vaccine Therapy. Its Theory and Practice. By R. W. Allen, M. D., B. S. (Lond.). Third edition. 1910. 8vo. 277 pages. P. Blakiston's Son & Co., Philadelphia.
The Diseases of Women. By J. Bland-Sutton, F. R. C. S. Eng. and Arthur E. Giles, M. D., B. Sc. Lond., F. R. C. S. Edin. Sixth edition, with 123 illustrations. [1909.] 12º. 554 pages. Rebman Company, New York.
Clinical Commentaries Deduced from the Morphology of the Hu- man Body. By Professor Achille De-Giovanni. Translated from the second Italian edition by John Joseph Eyre, M. Ry C. P., L. R. C. S. I., D. P. H. Cambridge. Part General. 8va? 436 pages. Rebman Company, New York.
A Text-Book of Mental Diseases. By Eugenio Tanzi. Authorized. translation from the Italian by W. Ford Robertson, M. D., C. M., and T. C. Mackenzie, M. D., F. R. C. P. Edin. [1909.]. 8vo. 803 pages. Rebman Company, New York.
Oxford Medical Publications. Practical Nursing for Male Nurses in the R. A. M. C. and Other Forces. By Major E. M. Hassard; R. A. M. C., and A. R. Hassard. 1910. 12°. 339 pages. Henry. Frowde, London; Hodder & Stoughton, London.
Oxford Medical Publications. Practical Obstetrics. By E. Hast- ings Tweedy. F. R. C. P. I., and G. T. Wrench, M. D. Second edition. 1910. 8vo. 491 pages. Henry Frowde, London; Hodder & Stoughton, London.
Oxford Medical Publications. History of Medicine. By Dr. Max Neuburger. Translated by Ernest Playfair, M. B., M. R. C. P., In Two Volumes. Vol. I. 1910. 8vo. 404 pages. Henry Frowde, London; Hodder & Stoughton, London.
The Lister Institute of Preventive Medicine. Collected Papers. No. 6. 1909-1910. 8vo. London.
Annual Report of the Sub-Department of Health Department of Public Safety. To the Mayor and City Council of Baltimore for the Fiscal Year ended December 31, 1909. 8vo. 243 pages .: 1910. Meyer & Thalheimer, Baltimore.
A Manual of Human Embryology. Written by Charles R. Bardeen, Herbert M. Evans, Walter Felix [and others]. Edited by Franz Keibel and Franklin P. Mall. In Two Volumes. Vo]- ume I. With 423 illustrations. 1910. 4to. 548 pages. J. B. Lippincott Company, Philadelphia and London.
Normal Histology. With Special Reference to the Structure of the Human Body. By George A. Piersol, M. D., Sc. D. 438 illustrations, many of which are in colors. Eighth edition. (Re-written.) [1910.] 8vo. 418 pages. J. B. Lippincott Company, Philadelphia and London. €
Lippincott's New Medical Dictionary. A Vocabulary of the Terms used in Medicine and the Allied Sciences, with their Pro- nunciation, Etymology and Signification. By Henry W. Cattell, A. M. (Laf.), M. D. (U. of P.) Freely illustrated with figures in the text. 1910. 8vo. 1108 pages. J. B. Lip- pincott Company, Philadelphia and London.
The Surgery of Childhood Including Orthopedic Surgery. E: De Forest Willard, A. M., M. D. (Univ. of Pa.), Ph. D. With 712 illustrations, including 17 in colors. [1910.] 8vo. ým pages. J. B. Lippincott Company, Philadelphia and London. Scientific Memoirs. New Series, No. 37. By Officers of the Medicai and Sanitary Departments of the Government of India. 1: vestigations on Bengal Jail Dietaries, with some Observa tions on the Influence of Dietary on the Physical Developmex: and Well-being of the People of Bengal. By Captain D. M .- Cay, M. B., B. Ch., B. A. O., I. M. S. 1910. 4to. 226 pages Superintendent Government Printing, Calcutta, India.
Cystoscopy as Adjuvant in Surgery. With an Atlas of Cystoscopie Views and Concomitant Text for Physicians and Students By Staff-Surgeon Dr. O. Rumpel. Only authorized English translation by P. W. Shedd, M. D. With 85 illustrations ir color on 36 plates and 22 texual figures. 1910. 4to. 131 pages. Rebman Company, New York.
The Priciples of Pathology. By J. George Adami, M. A., M. D. LL. D., F. R. S. Volume I. General Pathology. Second edition, revised and enlarged with 329 engravings and 19 plates. 1910. 8vo. 1027 pages. Lea & Febiger, Philadelphia and New York. -
Symptomatic and Regional Therapeutics. By George Howard Hoxie, A. M., M. D. With fifty-eight illustrations in text 1910. 8vo. 499 pages. D. Appleton and Company, New York and London.
Progressive Medicine. A Quarterly Digest of Advances, Dis- coveries and Improvements in the Medical and Surgical Sciences. Edited by Hobart Amory Hare, M. D., assisted by Leighton F. Appleman, M. D. Volume III. September, 191 .. 8vo. 338 pages. Lea & Febiger, Philadelphia and New York
A Manual of Hygiene and Sanitation. By Seneca Egbert, A. M., M. D. Fifth edition, enlarged and thoroughly revised. Illus- trated with 97 engravings. 1910. 12mo. 508 pages. Lea & Febiger, Philadelphia and New York.
A Treatise on Diseases of the Eye. By John Elmer Weeks, M. D. With 528 engravings and 25 full-page plates in colors. 1910. 8vo. 944 pages. Lea & Febiger, New York and Philadelphia
The Practice of Medicine. A Guide to the Nature Discrimination and Management of Disease. By A. O. J. Kelly, A. M., M. D. Illustrated. 1910. 8vo. 945 pages. Lea & Febiger, Phila- delphia and New York.
International Clinics. A Quarterly of Illustrated Clinical Lect- ures and Especially Prepared Original Articles. Edited by Henry W. Cattell, A. M., M. D. Volume III. Twentieth Series. 1910. 8vo. 311 pages. J. B. Lippincott Company, Phila- delphia and London.
Claims Arising from Results of Personal Injuries. The Relation Injury Bears to Disease and Disease to Injury. By W. Edward Magruder, M. D. 1910. 12mo. 26 pages . The Spectator Company, New York.
Pathogenic Micro-Organisms Including Bacteria and Protozos. By William Hallock Park, M. D., and Anna W. Williams, M. D. Fourth edition, enlarged and thoroughly revised. With 196 engravings and 8 full-pages plates. 1910. 8vo. 670 pages. Lea & Febiger, New York and Philadelphia.
The Essentials of Histology. Descriptive and Practical. By E A. Schäfer, M. D., Sc. D., LL. D., F. R. S. Eighth edition. 1910. 8vo. 571 pages. Lea & Febiger, Philadelphia and New York.
The Johns Hopkins Hospital Bulletins are issued monthly. They are printed by the LORD BALTIMORE PRESS. Baltimore. Subscriptions, a year (foreign postage, 50 cents), may be addressed to the publishers, THE JOHNS HOPKINS PRESS, BALTIMORE ; ringle copies will be send" mail for twenty-five cents each. Single copies may also be procured from the BALTIMORE NEWS CO., Baltimore.
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BULLETIN
TIAT RECEIVED
OF
E JOHNS HOPKINS HOSPITAL
Entered as Second-Class Matter at the Baltimore, Maryland, Postoffice.
.- No. 239.]
. BALTIMORE, FEBRUARY, 1911.
[Price, 25 Cents
CONTENTS.
PAGE
PAGE
ne Herter Foundation. (Illustrated.) FESSOR HANS CHIARI, M. D.
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cidosis.
F. A. MAGNUS-LEVY ·
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tions on the Bacteriology of the Baltimore City
Peri-Tonsillar Abscess
By MACTIER WARFIELD, M. D.
60
LIAM W. FORD, M. D. 53
ngenital Deformities (Patent Ductus Botalli: Ab- Left Kidney and Chronic Peripheral Œdema). (Illus-
Summaries or Titles of Papers by Members of the Hospital or Med- ical School Staff Appearing Elsewhere than in the BULLETIN 61
Notes on New Books .
64
LECTURES ON THE HERTER FOUNDATION .*
By PROFESSOR HANS CHIARI, M. D., Professor of Pathological Anatomy, University of Strassburg, Germany.
LTION OF THE AMNION TO THE ORIGIN OF HUMAN MALFORMATIONS.
iologist would discuss the relation of the amnion of human malformations, he must base his views e gathered from pathological anatomy. He must ly the cases in point that he may recognize the luences which the amnion can exert. He must ously to ascertain causes for these pathological Finally, from his own experience and that of d in the literature, he must gain a correct view e frequency of deformities which depend upon nd must contrast them with deformities which rent way.
to one denies that human malformations may her ways and quite independently of the amnion. w a child may inherit a deformity from either r its maternal ancestors: polydactylism illus- t. The cause for such malformations exists in -either ovum or spermatozoon. Again, some embryo may occasion malformation which is pathological collections of fluid within the body anhydrops). Occasionally, the umbilical cord the Medical Department of the Johns Hopkins ber 5, 6, 7, 1910.
or the second ovum where there is a double pregnancy, will exert a teratological influence. We also know that an injury directed against the abdomen of a pregnant woman may bring about fœtal malformation. To demonstrate the efficiency of this last influence I will relate the history of a case which I saw in the year 1881, while in Vienna, and which was published by Anton. The infant was a boy who died when fourteen days old. The autopsy revealed an imperfect corpus callosum ; persistence of the embryonic median furrows of the cerebrum with microgyria; hair lip and cleft palate; and a fracture of the right femur which had healed in utero. The period at which the defect in the corpus callosum must have originated was the beginning of the fourth month of pregnancy. At this time, moreover, according to the mother's history, she had sustained an injury, falling on the ice in such a way as to receive the brunt of the blow upon her abdomen. This had caused the fracture of the femur, and favors Anton's view, that the same injury caused not only breaking of the bone, but also malformation of the brain. The pathologist who studies human malformations of amniotic origin, must do so in the light of both comparative pathology and experimental teratology. But he will be very careful in adopting their teaching, since the origin and significance of the amnion are not the same in man and in the lower animals.
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Transverse Fracture of the Body of the Ischium in 1898; Termi- nal Displacement in 1902; Diagnosticated in 1909. (Illus- trated.)
By NORVELLE WALLACE SHARPE, M. D 57
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JOHNS HOPKINS HOSPITAL BULLETIN.
[No. 239
I have had opportunity to study an unusually large number of human malformations. The cases, I shall bring to your attention are selected from this material, which was secured at the Universities of Prague and Strassburg.
By far the most common human deformities of amniotic origin are those caused by " Simonart's bands." These string- like portions of amnion usually pass from that membrane to the embryo. A great deal has been written about the mal- formations they cause. Such deformities represent widely different types, including hair lip, cleft palate, micrognathia; fissure of the face, of the brain, of the spinal cord; fissure of the thorax and of the abdomen; constriction of the penis, and malformation of the extremities .* These bands run not only from the amnion to the fœtus, but may pass from one part of the surface of the foetus to another. It has been satisfactorily demonstrated that subsequent development of the embryo or fœtus may cause the amniotic bands to disappear after they have produced deformity ; hence their previous existence may be attested at the time of birth only by the damage they have worked.
I am indebted to Professor Kretz for permission to use the following cases from the Pathological Museum at Prague :
Fig. 1 shows both hands of a nine-month fœtus with pero- dactylia caused by Simonart's bands ; in other respects it was normal. On the left hand the fourth and fifth fingers, on the right hand the third, fourth and fifth fingers are imperfectly formed; the fingers mentioned on the right hand are not separated from one another. Remains of amniotic threads are seen on both hands, adherent to the affected fingers. We were unable to examine the placenta.
I have found the same kind of deformity in a woman seventy years old, and in her case the deformity was certainly caused by amniotic threads (Fig. 2). The right hand pre- sents atrophy of the fourth and fifth fingers; the left hand, atrophy of the fourth and fifth fingers, together with a de- fective nail on the fifth finger, a deep dorsal furrow on the fourth finger, a rather deep furrow on the back of the first phalanx of the third finger, and a furrow on the back of the second phalanx of the index finger. These deformities were all present at birth.
In proof of the fact that amniotic bands may cause con- striction about more proximal parts of the extremity, I offer, as an example, the case pictured in Fig. 3, which is that of an infant who died when three hours old. It presented fissures of the brain and of the face. The left hand showed indentations upon the third, fourth and fifth fingers; absence of the nail phalanx of the fifth finger, at the ulnar edge of which there still hung a remnant of an amniotic thread. On the right side, and about 1 cm. below the elbow, a deep circular fissure was found; the constriction reached the neighborhood of the bones of the forearm. At this point the skin was rent and the bones were broken as the result of injury at the time of birth. Distalwards from this circular fissure were found the remains of an extremity. It measured 5 by 3} cm., had an oval shape, and was covered with skin. This structure cor-
responded to the upper arm and the hand. It was markedl; œdematous, and at its peripheral end bore four digits; three of them, namely, the fourth and fifth fingers and the thumb. were well formed, except that the nail on the last was lacking. All were of normal size. The second finger was represente! by a short, pyramidal projection of skin without any nail, and had been drawn upwards and outwards to the side of the thumb. Amniotic threads joined- the above mentioned con- striction in the forearm to the rudimentary finger, and held the latter as would a sling. The third finger was entirely lack- ing.
It would have been only a step from this deep circular fissure formation to complete intrauterine amputation of the right forearm. In this instance also, we had no opportunity to examine the placenta.
Much less frequently, amniotic bands are found attached to other parts of the body. Fig. 4 shows a shrivelled, sixth- month fœtus papyraceous, which had died sometime before birth. Amniotic adhesions appear on the head. A band 4 cm. long and 2 mm. thick extended from the skull of the foetus to a point on the placenta near the insertion of the umbilical cord, and was twisted in a spiral about the latter structure. A club-shaped appendage was found in the region of the large fontanelle, immediately in front of the amniotic band with which it was connected. The appendage was 1 cm. long. and 5 mm. thick at its free end. It was covered with skin. contained a cavity which could be traced through its pedicle into the cavum cerebri, and clearly represented an encephalo- cele. The periphery of the placenta had involuted and con- pletely atrophied; but for that, the amnion presented it: normal characteristics.
In this case, then, we have seen an amniotic band attached to the head of an embryo and an encephalocele produced through the traction thus occasioned. Moreover, fotal death was very likely the result of its action, since constriction of the umbilical cord by the band would seem to account for that event.
Figure 5 represents a case of schizosoma caused by amniotic bands. The fœtus was about 38 cm. long. A short, ribbon-like band of amnion passed from the region of the navel to the back of the fœtus and had drawn along a tongue-shaped pro- jection of skin with a small, round cutaneous appendage upon it. In consequence of this band, several deformities had arisen, namely, a deep transverse furrow across the back; im- perfect closure of the pleuro-peritoneal cavity on the right side; protrusion of the viscera; and defective formation e. the right upper extremity. There was no umbilical cord. The umbilical arteries and the umbilical vein issued from the lower edge of the abdominal fissure. These vessels were closely approximated, and ran to the placenta surrounded by a very small quantity of Whartonian jelly, which in turn was encased in amnion. The other malformations noted in this specimen were a median fissure of the thumb; talipes varus with hep- tadactylia on the left side and talipes valgus with hexadactylis on the right. A few amniotic threads hung upon the right
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* See Von Winckel.
amnion which covered the placenta exhibited a few eads, scattered here and there over its inner surface.
illustrates the group of cases in which amniotic from one part of the fotal body to another. This :0 cm. long and of the male sex. An encephalocele, zontal circumference of 22 cm. appeared upon the skin covering it was very thin; the hernial opening wide; the cavity within the skull was quite small. tho-palatoschisis appeared upon the right side of From the chiloschisis a fissure ran upwards through alf of the nose to the anterior edge of the hernial A thread-like cord 10 cm. in length was attached at point, and ran toward the right axilla, where it o three parts, one of which was attached to the id one to the posterior axillary fold; the third was the back near the lower angle of the right scapula. 'e, the right hand was deformed; the fingers from to the fifth were small, malformed, without nails cted by manifold, delicate amniotic threads. The f the fourth finger on this hand had turned black. oot showed a valgus, and the left a varus position. a was not obtained.
ical anatomy also teaches that the mediation of bands is not the only way in which the amnion sally related to fotal malformations; abnormality of the amniotic cavity, and particularly a diminu- f reacts harmfully upon the development of the ases of this sort have been recorded by Marchand and e. In the case reported by Marchand, the embryo l six to seven weeks' development. Adhesions were t there was also a particularly defective amnion. ugh the latter anomaly that the embryo had suf- tive deformation. A continuous layer of amniotic was seen upon the inner surface of the chorion. attributed this either to a late proliferation of im from the point where the amnion had rup-
cleavage between the amnion and the chorion. ase pertained to a seven-month fœtus, in which ab- 'acture of the amnion had caused unusual bending extensive adhesions of different parts of the body, of malformations.
nection, I am able to add another case, illustrated ad 7b. This specimen consisted of a 34 cm. long, , which presented fissure of the face, a scar to- two cylindrical cutaneous appendages upon the skull and perodactylia of both hands as well as oot ; from the digits of the last remains of am- ns hung. Moreover, in this specimen we found Iving the abdomen and the lower part of the , of the abdominal organs and the left lung ugh the opening. The trunk of the fœtus was narrow, and gave the impression of having been corset. A thick, net-like covering of amnion, hy apertures, was fitted closely about the body, Therent save at the edges of the fissure. The entered at the right edge of the abdominal
fissure. This structure was 13 cm. long, and was inserted upon the margin of the placenta, which had a diameter of 17 cm. The amniotic covering of the placenta, and indeed of the entire inner surface of the chorion was lacking. Microscopical study verified that fact, showing only a few delicate thread- like remnants of the membrane. The short umbilical cord was entirely covered by amnion.
From the findings in this specimen, the conclusion is un- avoidable that the schizosoma had been produced by diminu- tion in the size of the amnion. The body of the embryo had been surrounded by a closely applied corset which interfered with the closure of the pleuro-peritoneal cavity. The mem- brane had become detached in the neighborhood of the head and the extremities; these regions were separated from the rest of the amnion. Malformation of the head and extremities had been caused by Simonart's bands, remnants of which were attached to the inner surface of the chorion.
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